With more and more prominence on the green transition, it is becoming increasingly important to find holistic resource efficient processes to replace traditional fossil-based systems. One such industry is the polymer foam industry which today relies heavily on polystyrene, polyurethane, polyethylene etc. which are synthesized from petroleum. Naturally, these foams are non-biodegradable and derived from non-renewable resources. Foams have been produced in several studies using nanocellulose and cellulose composites, however these reports do not offer a systematic study to establish the range of fiber properties that are necessary to acquire a stable foam, neither application of green and sustainable tools for adding bioactive properties to the foam end-product, potentially enabling their use in a wide range of niche applications such as in the pharmaceutical and food industry. Aim of our work is the formation of stable cellulose foams functionalized by a bioactive molecule: ferulic acid. To create this, a two step approach was followed: Coating of cellulose fibers with a high charge density cationic polymer i.e. PolyDADMAC, to create an environment that would be a good basis for efficient functionalization, and  further functionalization of cellulose fibers with ferulic acid using laccase as biocatalyst. The processing conditions for both steps were optimized i.e. substrate ratio, time, pH, temperature, enzyme load etc. targeting highest antioxidant activity of the functionalized fibers. The pulps were also characterized for their foaming stability and capacity and for their mechanical properties and hydrophobicity, establishing a thorough mapping of the effect of processing conditions over the final foam properties. This work is the first report on using enzymes for producing bioactive cellulose foams, showing the pathway for an efficient and low waste strategy for the production of high-added value materials based on cellulose from wood.